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Blog

Learn the system, not the shortcut

Plain, cited explanations of the physiology behind how you feel. No molecules, no dosing, no shortcuts being sold.

The Guide · Hormone and vitality

How resistance training supports healthy testosterone

Strength training changes body composition, sleep and insulin sensitivity, and all three interact with hormonal health. What the evidence supports, and what it does not.

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Biomarker Explainer · Metabolic health

Understanding ApoB and metabolic risk

Apolipoprotein B counts the particles that can lodge in an artery wall. Why a count often tells you more than a concentration.

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The Basics · Hormone and vitality

The basics of hormone health as you age

What actually changes, on what timescale, and why symptoms alone are a poor guide to what is going on.

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The Guide · Longevity and recovery

Sleep, recovery, and healthspan

The least glamorous input with some of the strongest evidence behind it, and what to do when the obvious advice has not worked.

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Biomarker Explainer · Metabolic health

Understanding HbA1c and what it misses

A three month average of blood glucose, useful and genuinely limited. What it tells you and what slips past it.

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The Basics · Longevity and recovery

Cardiorespiratory fitness, and why it keeps showing up

One of the strongest associations with long term mortality in the literature, and it is trainable at any age.

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The Guide · Longevity and recovery

Protein, muscle, and staying capable

Lean mass is not vanity. It is the buffer that decides how well the last decades go, and it needs both a stimulus and material.

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Biomarker Explainer · Metabolic health

Visceral fat, and why where it sits matters

Not all fat behaves the same way. The fat around your organs is metabolically different from the fat under your skin.

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The Basics · Hormone and vitality

Stress, cortisol, and what the word actually means

Cortisol is essential, rhythmic and widely misdescribed online. A short primer on what it does and what testing it can and cannot tell you.

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The Guide · Metabolic health

How to read a lab report without scaring yourself

Reference ranges are population statistics, not personal verdicts. How to look at your own results sensibly.

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The Guide · Longevity and recovery

How alcohol affects sleep, hormones, and metabolic health

One input touches all three of the areas this site covers, and most people underestimate it because the effect shows up the next day rather than the same night.

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The Guide · Longevity and recovery

Building health habits that actually stick

Most health plans fail at adherence rather than at design. What the behavior change research says about making a change survive past the first month.

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The Guide · Longevity and recovery

Exercise and the postmenopausal brain: what the science shows

A look at how movement supports cognition after menopause, the biology behind the benefit, and which types of exercise appear to help most.

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The Guide · Metabolic health

Why body composition beats scale weight for metabolic health

A look at how visceral fat, lean mass, and waist circumference shape metabolic and hormonal health, and why the number on the scale tells only part of the story.

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The Guide · Longevity and recovery

Strength as longevity medicine: what the 2026 guidelines confirm

New 2026 cardiac guidelines reaffirm that heavier resistance training and adequate protein are the core of muscle-centric aging. Here is what that means for your week.

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The Guide · Longevity and recovery

The real drivers of recovery: sleep, protein, and smart rest

The strongest evidence for recovery in healthy adults points to sleep, adequate protein and energy, and structured light activity. Supplements lag far behind.

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The Guide · Longevity and recovery

Tryptophan, mood and inflammation: what the biology actually shows

A look at how your body divides tryptophan between serotonin, kynurenine and microbial routes, and why inflammation may shape that split in mood biology.

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The Guide · Longevity and recovery

What your wearable can and cannot tell you about fitness

Cardiorespiratory fitness and grip strength predict healthspan, but wearables only approximate them. Here is how to read the numbers on your wrist.

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The Guide · Understanding your labs

Reading CGM data when you do not have diabetes

Continuous glucose monitors can reveal useful patterns in daily glucose, but in people without diabetes they are not standalone diagnostic tests. Here is how to read the data sensibly.

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The Basics · Longevity and recovery

What a peptide is

A peptide is a short chain of amino acids. It is smaller than a full protein, and it is not automatically a drug.

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The Guide · Longevity and recovery

Why I started SiriusRx

Eating well, training, and a cabinet full of supplements were already the routine, and nothing felt like a result I could point to. I started SiriusRx to help close that gap.

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Formats

The Guide
Longer reads that connect a topic to what you can actually do about it.
Biomarker Explainer
One marker at a time: what it is, why it matters, what moves it.
The Basics
Short primers, no assumed background.

Also here

Looking for the lab reference?

The plain-language table of the markers that come up in this space now lives on the Resources page, alongside the rest of the reference material.

Understanding your labs